In Sacrifice, 5 players take turns placing cubes in a grid, hoping to score many points. Players may only place a cube in the left-most empty space of a row. Some spaces require a player to remove other cubes they have placed. Once every space on the board is full, the game ends and players are awarded points based upon the spaces they occupy, with a bonus in each row for whomever has the most and second-most cubes. The player with the most points wins. The game also includes a variant for 4 people to play with a non-player character taking the fifth color.