Rogue Legacy

Rogue Legacy is an indie game platformer with roguelike elements. Whenever a character dies as a result of losing all of their Hit Points (HP), control will transfer over to one of three randomly generated heirs, each with their own unique characteristics and abilities. Such genetic peculiarities include color-blindness (in which the game is presented in black and white), ADHD (in which the player moves faster) and dwarfism (in which the character is short and can fit into small gaps). Source: Wikipedia, "Rogue Legacy", available under the CC-BY-SA License.