Potion 21

Potion 21 combines roguelike elements such as randomly generated dungeons and permadeath with a game everyone already knows: blackjack, making it a great entry-level tabletop game. Each round consists of constructing a dungeon and getting as far as you can without overdosing on potions (the equivalent of "busting" in blackjack) or being killed by monsters (the equivalent of having a lower score than the dealer). As the game progresses you get better potions and raise your starting power, but when you die you lose everything and start the whole game over. The first player to collect 3 immortality potions win the game! —description from the publisher