Pirates of the Spanish Main: Shuffling the Deck is set in the environment of the Pirates of the Spanish Main constructible strategy game, features artwork from that property's many releases, and employs "a new card game system that uses a simple and fun twist" on that game. During play, you want to steer the captains that you sponsor and their ships to treasure, but you need to be discreet about who you sponsor. If another player guesses which ships are yours, he gets to plunder half your gold!