Opus Magnum, The Philosopher's Stone

"Card Game for 2 or more players. Players are 17th century alchemists, competing for the creation of the Philosophers Stone." The game uses a custom deck containing three types of cards: Elements, Procedures, and Substances. Elements and Procedures must be combined to create Substances, which in turn can be combined with Elements, Procedures, or other Substances to create more complex Substances. "The first player who creates the 'Resurrected Lapis Philosophorum' wins."