Currently, various infectious diseases are spreading around the world. Players participate in the game as part of the CDC and must quarantine and treat infected patients in the most efficient way. The goal of the game is to prevent the spread of infectious diseases among flares distributed in each city. The first player in each round starts with a vaccine card. He throws all the dice and selects one set of the same scale dice in one color in the order of play and takes them. Each round proceeds in the order of the next three steps. dice rolling (infection and research), dice distribution (allocation), and worksheet writing (isolation and treatment). All players share all the dice in order until they disappear, and fill out their own worksheet paper. (Players who take the dice must immediately record all the dice scales they took into the worksheet.) When all players finish writing the worksheet, the round ends with isolation treatment. The next player will take the vaccine card and become the first player to proceed with the new round. If the following situation occurs while playing several rounds, the game ends after playing the round: a player fills up both the infected patient and the vaccine treatment section in two wards, Or if a player O marks his third time in a space where he's in a worksheet or a shortage of hospital rooms. When the game is over, the player with the highest total wins by calculating each of the following scores: Treatment score, infection patient score, vaccine treatment inventory score, infection eradication score, vaccine treatment acquisition rate score, and hospital room shortage score.