"Each player takes the role of a Heart Patient. Object: Be the patient to live the longest." The game uses a custom deck of cards consisting of six types: Medical Interventions, Lifestyle Modifications, Surgery, Pathological Events, Drug Therapies, and Heart Attack Cards. Each player rolls up a character/patient to establish seventeen "risk factors", which include items such as Family History, Cholesterol Levels (LDL, HDL, and Total), Weight, Diabetes, Alcohol, and Smoking.