In DeZpair: 24 horas de deZespero, a band of mercenaries tries to rescue the survivors of a zombie-infested city before the military "cleans up" the place with a nuclear bomb. You have 24 hours to swipe the city clean of people before the bomb explodes! The game uses a modular board made of tiles to model the city search and zombie attacks, with custom dice used for character skills. Players use the dice to fight the zombies, search for survivors, and loot anything that the previous citizens left behind before joining the undead horde. The tiles show how many zombies are in a location, and the game unfolds through the exploration of these tiles.