Cleopatra Against the Gods is a skirmish game with mythological theme. "The mortals have been chosen. Soon new Gods will arise. War will come from chaos, and only a new Hierarchy will be able to save us." In Against the Gods, you will have control over two Deities of the Ancient World, which must synergize to defeat the rest of the Gods. Choose your move very well, an error and your Alliance could be left out of the New Order. Each Deity has a preconstructed deck of cards. By joining the decks of two Deities, the strategy and the gameplay increase exponentially. Against the Gods is a competitive game, so the combat results in an all against all. To use the effect of cards, you must roll certain number combination with your four d4. You can reroll up to twice, and use cards to influence your dice. If you get the results required by your deity, you inflict damage on your opponents. The winner is the last player who survives the battle.