Chaos & Alchemy is a fast-paced game of laboratory building and rivalry between alchemists. Players conduct an experiment each turn by rolling 3 dice, hoping for each die to be at least as high as the shared Fortune Die. Each success lets the alchemist draw a new card from the deck or play a card from hand; each failure means a discard. Cards represent Innovations to improve the alchemist's laboratory, Misfortunes to make rivals' lives harder, Actions to immediately impact the game, and Reactions to respond to other alchemists' deeds. When an alchemist rolls doubles in an experiment, Chaos occurs and fortunes change. The experimenter re-rolls the Fortune Die, making success easier or harder to achieve. Players race to build up a laboratory sophisticated enough to turn lead into gold. The first player with 10 or more points of Innovations in the laboratory is the victor! Rule clarification: A standard experiment involves rolling 3 dice (this is unclear in the Second Edition rulebook).