Bio Maniac is an educational card game about curing and preventing diseases. It consists of cards for diseases and cures, plus event cards. In a turn, a player flips open five cards from the deck, cures diseases with the appropriate cards (if these are available) and hands out the remaining cards to other players who can use them in subsequent turns. At the end of the game, players gain points for cured diseases, with more points being dealt out if a player has collected more than one disease card of the same type. Uncured diseases score negative points. The player with most points wins the game.